Human Papillomavirus (HPV) Infection Vaccines Offer Protective Immunity Against Certain Viruses Which can Cause Genital Warts and Cervical Cancer


HPV is one of the most common sexually transmitted diseases in the United States and worldwide. It causes genital warts, a cancer called anogenital squamous cell carcinoma (ASC), and cervical precancerous lesions known as anogenital intraepithelial neoplasia. About 31,000 HPV-related cancers are diagnosed each year in the United States, most of which could be prevented with an HPV vaccine Vaccines are the most effective prophylactic (prevention) vaccines available and have established several important vaccinologic landmarks, including induction of sterilizing immunity from initial infection for at least a decade without booster vaccination. They also appear to induce long-term stable serum antibody responses that may be associated with a reduction in the frequency of anogenital squamous cell cancer.

Women of all ages should be vaccinated with an HPV vaccine to reduce the risk of HPV infection, genital warts, and cervical cancer. The vaccines currently recommended by the Advisory Committee on Immunization Practices protect against all types of HPV, including those that cause anogenital squamous cell and cervical cancer, as well as genital warts. When an HPV vaccine is administered to all women, the vaccine effectively prevents the majority of genital warts caused by certain HPV types. The vaccine has been found to be significantly effective in reducing the incidence of other HPV-associated diseases such as anogenital cancer and anogenital squamous cell neoplasia.

According to Coherent Market Insights the Human Papillomavirus (HPV) Infection Vaccines Market Industry Insights, Trends, Outlook and Opportunity Analysis, 2022-2028.

There are many different types of HPV and each type has a specific molecular profile that can trigger certain cancers. Vaccines can protect against all HPV types, as they are most effective against those types that cause most cancers in the United States. The most common and effective types of HPV are the ones that cause anogenital squamouscell carcinoma and genital warts. In the United States, genital warts and anogenital cancer are the most common manifestations of HPV-related disease in women and men, respectively. In fact, about 90% of all genital warts are caused by types 6 and 11 of the HPV virus, which are both covered by the vaccine.

Some studies have suggested that an HPV vaccine might be beneficial in children with this disease, particularly those who have been exposed to an infected mother during birth or in the first few years of life. In June 2022, Serum Institute of India announced to launch India’s first indigenous human papillomavirus vaccine by November 2022. This is the country’s big push against cervical cancer.

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