Vitiligo Drugs Can Help In Restoring Some Amount of Skin Color and Also Help in Preventing New Spots from Forming


Vitiligo is a condition in which white spots of pigment-producing skin cells appear on parts of the body. The spots vary in size, shape and color. They often show up on the face, hands and feet. They can also affect hair, eyes and the inside of the mouth. It's not contagious, and the cause is unknown. It has been linked to autoimmune diseases and stress. People with vitiligo can be stigmatized, especially when it appears on the hands and face. The condition can affect a person's mood, too.

There is no way to stop vitiligo from spreading, whereas treatments can help camouflage it or return pigment to the skin. A doctor can perform a skin graft to move healthy pigment from a more pigmented part of the body and cover the areas where vitiligo has spread. Another treatment involves a medical tattoo that transfers normal pigment to the affected area. A special type of this procedure, called micropigmentation, can be better for darker skin tones than other techniques Vitiligo drugs can restore some skin color and help prevent new spots from forming. It may take months or even years to judge whether a treatment is effective. And even if a drug works, it's possible that the vitiligo will return. And some patients don't respond to any treatment.

The global Vitiligo Drug Market is estimated to be valued at US$ 151.9 million in 2020, and is expected to exhibit a CAGR of 12.6% during the forecast period (2020-2027).

A new drug, ruxolitinib cream (Opzelura), from Incyte, is the first FDA-approved treatment specifically for vitiligo. It is used topically and helps people with nonsegmental vitiligo, the most common type of the condition. It works by tamping down the immune system and encouraging it to grow more pigment-producing cells. It is an option for those who haven't had much success with phototherapy, which can be expensive and time-consuming and can cause sunburns in some people Pimecrolimus and tacrolimus, which are usually given orally and have been available for some time, can also help restore skin pigment. They can be used alone or in combination with UV light. However, some research suggests that they might not be as effective as phototherapy. They can cause thinning of the skin in some people.

Other treatments include using an excimer laser to target specific areas. This can be costly, and it doesn't work as well in darker people. Phototherapy uses narrow-band ultraviolet B light to treat the condition. This can be done in a doctor's office or at home. It can be painful, and it's not safe to use for too long, due to the risk of skin cancer. Maruho Co., Ltd., and Incyte declared their Strategic Alliance Agreement in April 2022, for manufacturing, developing, and commercializing ruxolitinib cream.

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